Pdf treatment planning for volumetric modulated arc therapy. Volumetric modulated arc therapy vmat in the treatment of a patient with prostate cancer 2 patient history and diagnosis this is a 62yearold white male that was diagnosed with prostate cancer in late 2010. Effective heartsparing whole lung irradiation using. Pdf application of volumetric modulated arc therapy. Pdf volumetric modulated arc therapy vmat is a novel radiation technique, which can achieve highly conformal dose distributions with improved target. However, gating significantly prolongs treatment time. Dose verification of volumetricmodulated arc therapy. Volumetric modulated arc therapy vmat in the treatment of esophageal cancer patients article pdf available in medical oncology 3512 december 2018 with 255 reads how we measure reads. Apr 14, 2014 differences in isodose distribution between intensity modulated radiation therapy imrt in the eclipse treatment planning system and volumetric modulate arc therapy vmat in the monaco treatment planning system. Pdf volumetric modulated arc therapy versus intensity.
A total of 20 cases of gynecologic malignancies were included. Volumetric modulated arc therapy vmat for hippocampal. Volumetricmodulated arc therapy for leftsided breast cancer. Sparing cardiac substructures with optimized volumetric. We also wanted to determine how a cardiac optimization treatment planning algorithm influences dose distribution to.
Impact of positioning errors in the dosimetry of vmat left. The role of volumetric modulated arc therapy vmat in. Volumetric modulated arc therapy vmat peter maccallum. Volumetric modulated arc therapy treatment planning of. Volumetric modulated arc therapy vmat cleveland clinic. Dosimetric comparison between the prostate intensitymodulated radiotherapy imrt and volumetricmodulated arc therapy vmat plans using the planning target volume ptv dosevolume factor volume 15 issue 3 james c. With volume modulated arc therapy, doses of radiation are delivered to the patient in an uninterrupted arc around the patient, greatly reducing the time of treatment. Volumetric modulated arc therapy is a novel form of treatment in the era of modern radiation oncology dealing with fast and rapid treatment of cancers.
Then, linac parameters were converted into the beamdata format used in the treatment planning system. Volumetric modulated arc therapy for prostate cancer m. Volumetric modulated arc therapy vmat is a novel form of intensity modulated radiation therapy that allows the radiation dose to be delivered in a single gantry rotation using conformal or modulated fields. Purpose total scalp irradiation tsi is a rare but challenging indication. A pubmedmedline search of the national library of medicine was performed to identify vmat and breast related articles.
Volumetric modulated arc therapy versus intensity modulated radiotherapy for large volume retroperitoneal sarcomas. A volumetric modulated arc therapy vmat beam arrangement has previously been proposed for breast cases, where the chest wallbreast is treated with a limited angle partial arc tangential vmat. We sought to evaluate the ability of optimized volumetric modulated arc therapy vmat and intensity modulated proton therapy impt to spare cardiac substructures. Optimization methods for volumetric modulated arc therapy and radiation therapy under uncertainty by fei peng a dissertation submitted in partial ful llment of the requirements for the degree of doctor of philosophy industrial and operations engineering in the university of michigan 20 doctoral committee. A dosimetric comparison of double arc volumetric modulated arc therapy with large field intensity modulated radiation therapy for head and neck cancer doi. Helical tomotherapy and volumetric modulated arc therapy. The earlier form of arc therapy, termed intensity modulated arc therapy imat was first described by yu in 1995 and required the use of multiple superimposed arcs to achieve a satisfactory dose distribution. Dose verification of volumetric modulated arc therapy. Purpose volumetric modulated arc therapy vmat is a specific type of intensitymodulated radiation therapy imrt in which the gantry speed, multileaf. This esurvey was carried out to facilitate the implementation and education of vmat volumetric modulated arc therapy in radiotherapyrt departments and.
More recent vmat techniques have allowed the whole target volume to be treated using one or two arcs, although complex cases may require more. Volumetric modulated arc therapy vmat has found widespread clinical application in recent years. Nuclear medicine volume modulated arc therapy vmat. A dosimetric comparison of volumetric modulated arc. The clinical imrt plans of twenty gynaecological cancer patients were compared with a retrospectively generated vmat plan. Code of practice for the quality assurance and control for volumetric modulated arc therapy february 2015 this report was prepared by a subcommittee of the netherlands commission on radiation dosimetry ncs. Keratoacanthomas following definitive volumetric modulated. Optimization methods for volumetric modulated arc therapy. Volumetric modulated arc therapy vmat is a technique of intensity modulated radiation therapy imrt permitting improved planning target. Rapidarc always uses single arc to deliver treatment. Warrington, commissioning of volumetric modulated arc therapy vmat. Dose verification of volumetricmodulated arc therapy using. Volumetric modulated arc therapy improves dosimetry and reduces treatment time compared to conventional intensity modulated radiotherapy for locoregional radiotherapy of leftsided breast cancer and internal mammary nodes. Planning strategies in volumetric modulated arc therapy.
Imat is a rotational intensity modulated radiation therapy imrt which can be delivered using conventional linear. Anton mans danny schuring mark arends lia vugts jochem wolthaus heidi lotz marjan admiraal rob louwe. Imat is a rotational intensity modulated radiation therapy imrt which can be delivered using conventional linear accelerator with conventional ulti leaf collimators mlc. Shepard swedish cancer institute, seattle, wa purposeobjectives. Radiation pneumonitis in lung cancer treated with volumetric. Evaluation of the dosimetric advantage, if any, of rapidarc double arc and triple arc da and ta over standard fixed field intensity modulated radiation therapy imrt in gynecologic malignancies.
Volumetric modulated arc therapy vmat is a specific type of intensity modulated radiation therapy imrt in which the gantry speed, multileaf collimator mlc leaf position and dose rate vary continuously during delivery. A series of 17 patients with 2 to 5 brain metastatic lesions were studied. Dose verification of volumetric modulated arc therapy using onedimensional and twodimensional dosimeters volume 18 issue 3 jalil ur rehman, zahra syed, ghulam hussain, nisar ahmad, h m noor ul huda khan asghar, zaheer abbas gilani, gulfam nasar, malik m akhter, muhammad isa, tahir iqbal. This technique accurately shapes the radiation dose to the tumour while minimising the dose to the organs surrounding the tumour. Although arc therapy can be traced back to the dawn of the 20th century, arc therapy involving dynamic field shaping using a multileaf collimator was first described by takahashi in 1965.
Volumetric modulated arc therapy planning for distal. Collimator rotation in volumetric modulated arc therapy for craniospinal irradiation and the dose distribution in the beam junction region qilin li, wendong gu, jinming mu, wenming yin, min gao, juncong mo and honglei pei abstract purpose. Gated volumetric modulated arc therapy vmat is an emerging treatment modality for stereotactic body radiotherapy sbrt. Volumetric modulated arc therapy vmat treatment involves three basic steps. Intensity modulated arc therapy imat the evolution of. To evaluate how the use of volumetricmodulated arc therapy vmat with rapidarc can improve treatment delivery efficiency based on the. To compare variable doserate volumetric modulated arc therapy vmat with 7field, stepandshoot intensity modulated radiation therapy imrt in prostate cancer patients treated with a consistent planning target volume ptv to a uniform total radiation therapy dose. More recent vmat techniques have allowed the whole target volume to be treated using one or two arcs, although complex cases may require. Volumetric modulated arc therapy vmat is a novel radiation technique, which can achieve highly conformal dose distributions with improved target volume coverage and sparing of normal tissues compared with conventional radiotherapy techniques. Volumetric modulated arc therapy vmat for leftsided breast treatment, including lymph node irradiation involving the imc, was recently compared with mwt 6, 7, but never with a forwardplanned multisegment technique with a monoisocenter monoiso.
A total of 18 perturbations where introduced in 11 vmat treatment plans that shifted the isocenter from its reference position of 3, 5. A large number of treatment planning studies have evaluated the potential for vmat for different disease sites based on the currently available commercial implementations of vmat planning. Optimization approaches to volumetric modulated arc therapy. In conventional radiation therapy, a motion encompassing margin is normally added to the clinical target volume ctv to ensure the tumour receives the planned. Treatment of multiple brain metastases using stereotactic. Imrt for the treatment of distal esophageal cancer. Volumetric modulated arc therapy for treatment of solid tumors ncbi. Code of practice for the quality assurance and control for.
Volumetric modulated arc therapy vmat, formally known as intensity modulated arc therapy imat was introduced by cedric yu 1995b1. Vmatimrt are complex radiation treatments that are normally used for. The research aims to evaluate the impact of positioning errors in the dosimetry of vmat leftsided pmrt. Differences in isodose distribution between intensity modulated radiation therapy imrt in the eclipse treatment planning system and volumetric modulate arc therapy vmat in the monaco treatment planning system.
The purpose of this study was to investigate the role of beam collimator rotation in volumetric. Late cardiovascular diseaserelated adverse events are one of the most common causes of premature mortality among longterm survivors of childhood. Effective heart sparing is possible for whole lung irradiation using volumetric modulated arc therapy. Treatment planning for volumetric modulated arc therapy. The purpose of this work was to investigate whether the mobius3d v. To investigate the feasibility of partial arc volumetric modulated arc therapy vmat in lung cancer stereotactic body radiotherapy sbrt, as well the volumetric and dosimetric effects of different internal target volume itv definitions with 4d ct. Pdf the physics behind volumetric modulated arc therapy. Volumetric modulated arc therapy vmat combined with deep. Is volumetric modulated arc therapy rapidarc better than. There is a lack of research regarding breast irradiation after breastconserving surgery bcs using vmat with prone positioning. A comparative analysis of dosimetric and treatment delivery parameters. Volumetric modulated arc therapy vmat uses an aperturebased optimization technique, which minimizes both mu and radiation leakage. Collimator rotation in volumetric modulated arc therapy for. Intensity modulated radiation therapy and advanced rotational techniques such as volumetric modulated arc therapy have the potential to increase dose conformity and homogeneity and reduce treatment delivery times.
Volumetric modulated arc therapy vmat is an elegant technique of delivering imrt that allows for shorter treatment times achieved by optimizing mlc positions and dose rate while the gantry rotates around the patient with the beamon. Pdf clinical applications of volumetric modulated arc. Methods arc control points are created uniformly throughout one or more arcs. Volumetric modulated arc therapy vmat may be another approach to investigate improvement in these parameters. The capability of vmat to reduce heart and cord dose, while maintaining lung receiving 20 gy,20%, was evaluated for. Volumetric modulated arc therapy vmat is a novel radiation therapy technique that delivers the radiation dose continuously as the treatment machine rotates. Volumetric modulated arc therapy for prostate cancer pdf. Static imrt sliding window, single arc sa, da and ta plans were generated with eclipse planning system. Application of volumetric modulated arc therapy vmat in a dualvendor environment article pdf available in radiation oncology 51. Chow, runqing jiang, alexander kiciak, daniel markel. Optimizing laryngeal sparing with intensity modulated.
Both clinical and treatment planning studies were investigated. Dose verification of volumetric modulated arc therapy using onedimensional and twodimensional dosimeters volume 18 issue 3 jalil ur rehman, zahra syed, ghulam hussain, nisar ahmad, h m noor ul huda khan asghar, zaheer abbas gilani. Optimization approaches to volumetric modulated arc. Fourteen patients with primary and metastatic lung cancer underwent sbrt were enrolled. A novel 4d volumetric modulated arc therapy 4d vmat planning system is presented where radiation sparing of organs at risk oars is enhanced by exploiting relative target and healthy tissue motion induced by patient respiration. Optimization methods for volumetric modulated arc therapy and. Increasing radiation dose to the heart is associated with worse survival in stage iii nonsmall cell lung cancer.
A dosimetric comparison of double arc volumetric modulated. This consecutive treatment planning study compared imrt with volumetric modulated arc therapy vmat. In a community cancer center, treating prostate cancer comprises about one third of a typical practices volume. Volumetricmodulated arc therapy for leftsided breast. Largescale studies using standardized procedures should be conducted to validate our results. Volumetric modulated arc therapy vmat adopted in postmastectomy radiation therapy pmrt has the capacity to achieve highly conformal dose distributions. Vmat, considered to be similar to imrt was first described by yu et al. Anatomical features are identifiable on static phantom scatter images collected with 10 mu of delivered dose 2. For gynaecological cancers, volumetric modulated arc therapy vmat offers comparable plan quality with shorter treatment delivery times when compared to intensity modulated radiation therapy imrt. Several treatment modalities such as split or wholefield intensity modulated radiotherapy sfimrt, wfimrt and volumetric modulated arc therapy vmat are being used to treat tonsillar cancer patients with unilateral neck radiotherapy. Vmat also has the potential to offer additional advantages, such as reduced treatment delivery time. Istanbul, turkey abstract the success of radiation therapy depends on the ability to deliver the proper amount of radiation to cancerous cells. Volumetric modulated case study arc therapy vmat in the.
The determination of optimal treatment plans for volumetric modulated arc therapy vmat p. Target volumes coverage appeared better with vmat than with mwt. Intensity modulated arc therapy imat was proposed by yu as an alternative to. Plan quality and treatment planning technique for single. A four dimensional volumetric modulated arc therapy. Genesiscare provides vmatimrt to all patients at no additional cost and without delay to commencement of the treatment process. In breast radiotherapy with intensity modulation, it is a well established practice to extend the dose fluence outside the limit of the body contour to account for small changes in size and position of the target and the rest of the tissues due to respiration or to possible oedema. In dual arc conventional volumetric modulated arc therapy dac vmat, the large irradiation field for whole brain planned target volume ptv requires a wide jaw opening in which substantial low dose volume to the hippocampus may be produced due to suboptimal multileaf collimator. Critical appraisal of the role of volumetric modulated arc. Dosimetric comparison between the prostate intensity. A simple approach is not applicable with rapidarc volumetric modulated arc therapy not being based on a. Purpose volumetric modulated arc therapy vmat is a specific type of intensity modulated radiation therapy imrt in which the gantry speed, multileaf collimator mlc leaf position, and dose rate vary continuously during delivery. Pdf treatment planning for volumetric modulated arc. Linac parameters such as the multileaf collimator mlc position and jaw position, cumulative monitor units mus, and the corresponding gantry angle were recorded during the clinical delivery of volumetric modulated arc therapy for prostate, lung, and headneck cancer patients.
We previously reported that noncoplanar intensity modulated radiotherapy imrt was superior to coplanar imrt in organatrisk oar protection and target dose distribution. Volumetric modulated arc therapy vmat is considered to deliver a better dose distribution and to shorten treatment time. Dosimetric comparison between the prostate intensity modulated radiotherapy imrt and volumetric modulated arc therapy vmat plans using the planning target volume ptv dose volume factor volume 15 issue 3 james c. Clinical applications of volumetric modulated arc therapy.
Vmatimrt are complex radiation treatments that are normally used for complex cancers requiring targeted radiation treatment. As part of the diagnosis, the medical team generates threedimensional diagnostic images usually ct andor pet of the patients anatomy and then uses these images to specify the dose of radiation needed to treat the tumor. In dual arc conventional volumetric modulated arc therapy dacvmat, the large irradiation field for whole brain planned target volume ptv requires a wide jaw opening in which substantial low dose volume to the hippocampus may be produced due to suboptimal multileaf collimator mlc movements. Volumetric modulated arc therapy, based on the original investigation of otto 6 has been introduced in clinical practice in several institutes after an intensive validation at the planning level, compared with intensity modulated radio therapy imrt or other approaches. Considerations in bilateral lung treatment planning with.
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